Vitamin B12
Methylcobalamin / Cyanocobalamin
Key Benefits
Energy Production
Required for red blood cell formation and oxygen transport, preventing fatigue and weakness.
Neurological Health
Maintains myelin sheath integrity and supports cognitive function and nerve signaling.
DNA Synthesis
Essential cofactor for DNA replication and cellular division.
Mood Support
Involved in neurotransmitter synthesis, supporting mental health and mood regulation.
Activation Synergies
B12 and folate work together in homocysteine metabolism and DNA synthesis. Supplementing one without the other can mask deficiency.
Recommended Dosage
medical_servicesMethylcobalamin and adenosylcobalamin are active forms; cyanocobalamin requires conversion. Sublingual or intramuscular forms bypass absorption issues. Higher doses (1000mcg+) may benefit those with absorption problems.
Deficiency Indicators
- Extreme fatigue or weakness
- Tingling or numbness in hands/feet (paresthesia)
- Memory issues or brain fog
- Pale or jaundiced skin
- Shortness of breath or heart palpitations
- Glossitis (inflamed tongue)
Scientific Citations
Vitamin B12 Fact Sheet for Health Professionals
Vitamin B12: Research Summary
Status: In Your Stack Status: Not in Stack